The director's 2006 movie This Is England spawned TV follow-ups This Is England '86 in 2010 and This Is England '88 in 2011, but work on the 1990 catch-up was halted while Meadows made his documentary The Stone Roses: Made of Stone.
Asked if This Is England '90 would be his last part of the story, Meadows told Digital Spy: "Yeah, hopefully. I say hopefully because I don't want to end up ruining it, but I love the cast."
Producer Mark Herbert joked: "We should do This Is England '70, when they're at school!"
Meadows added: "This Is England the musical? Who knows!
"It's really hard to put down when you have so much fun doing something, so I hope I don't push it too far and I hope '90 is maybe a full stop, but I daren't say forever."
Asked about the themes of the final series, the director said: "The younger members of the crew, it becomes their time.
"Obviously Woody (Joseph Gilgun) and Milky (Andrew Shim) and Lol (Vicky McClure) were the genuine skinheads - and Combo (Stephen Graham) - the others attached themselves to it.
"In This Is England '90 it becomes about Shaun (Thomas Turgoose) and Kelly (Chanel Cresswell) and Trev (Danielle Watson) and Gadget (Andrew Ellis) actually getting into the Roses and getting into that scene and going clubbing and going raving and all of that."
He continued: "They sort of go off on that journey. Combo comes out of prison, he's served his time for manslaughter, and actually starts working in the community and the rehabilitation of his character begins.
"Woody and Milky set up a scooter shop. Woody finally gets out of that awful Mr Squire's factory that he's been working at, and him and Milky become really strong again.
"Everyone starts to do slightly separate things, but it's still got that beautiful unity that the others have all had. So, I've got the stories all lined up in my head, but I just need to get them down on paper."
Watch Joe Gilgun talk about the success of This is England in the video below:
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I CANNOT WAIT