TV vet Marc Abraham and Queen guitarist Brian May with the PUP AID Guitar.
Brian May, Jimmy Page, Keith Richards and Roger Daltrey have signed a guitar to help dogs.
The rock legends are among several stars - including Pink Floyd's David Gilmour, Eric Clapton, Paul Weller, Mick Jones and Thin Lizzy's Gary Moore - to put their signatures on the PUP AID Epiphone Casino Guitar, which was donated by Liam Gallagher and will be auctioned off later this month.
TV vet Marc Abraham is responsible for the anti-puppy farming initiative and is delighted so many famous faces have agreed to lend their support to the PUP AID Campaign.
He said: "I'm so thankful to Epiphone for starting what's been quite a mad journey, and truly honoured to have met some of the most influential musicians and heroes in rock history who have supported this campaign."
PUP AID is also being backed by Save-Me - a campaign founded by Queen guitarist May to promote decent treatment of animals - who have urged dog lovers to back responsible pet breeding.
They said: "Save-Me is supporting Marc the vet's important campaign to end the disgraceful Puppy Farming trade. Make sure you don't support cruelty in irresponsible pet breeding."
The PUP AID Epiphone Casino Guitar will be sold at London's Bonhams on December 15, along with an original Jimi Hendrix guitar and Beatles lyrics in a special entertainment memorabilia auction.
Proceeds from the sale will go to the Dogs Trust, Oldies Club - a charity specialising in rehoming older dogs - and the Kennel Club Charitable Trust.