Morrissey appears to have taken offence at The Simpsons after being sent up in the animation's latest episode, titled Panic On The Streets of Springfield, Lisa Simpson becomes obsessed with the militantly vegan singer of a 1980s indie band.
But her dreams are shattered when it transpires her idol, voiced by Benedict Cumberbatch, had become a bitter, overweight, anti-immigrant meat-eater.
A statement on Morrissey's Facebook called the show "hurtful and racist".
"Surprising what a 'turn for the worst' the writing for The Simpson's TV show has taken in recent years," said the statement, which was posted by the star's manager, Peter Katsis.
"Poking fun at subjects is one thing," it continued, "but when a show stoops so low to use harshly hateful tactics like showing the Morrissey character with his belly hanging out of his shirt (when he has never looked like that at any point in his career) makes you wonder who the real hurtful, racist group is here.
"Even worse - calling the Morrissey character out for being a racist, without pointing out any specific instances, offers nothing. It only serves to insult the artist."
In recent years, Morrissey has been criticised for his controversial views.
He has called halal meat "evil", accused London Mayor Sadiq Khan of being unable to "talk properly" and appeared to defend actor Kevin Spacey over allegations of sexual abuse.
The singer has also expressed support for the far-right For Britain party, wearing a badge with its logo on it during a US TV performance.
He has consistently denied being a racist.
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