Friday's gross included in Thursday evening previews.
Hustlers rustled up a strong $13.1 million from 4,570 theaters for a projected domestic debut of $32 million.
It: Chapter Two, which is on course to earn $40 million or more in its sophomore outing.
The Goldfinch earned a measly $870,000 from 2,542 theaters on Friday for a projected $2.6 million weekend.
The Goldfinch cost a reported $45 million to produce.
It bombs in one of the worst starts ever for a movie opening in more than 2,500 cinemas.
Hustlers is the best start ever for STXfilms and the best live-action opening of JLopez's careeer.