Hitting out on Twitter about Kim Kardashian's daughter North West, the businesswoman dubbed the one-year-old "ugly".
"North West. If there's one thing worse than an ugly baby, it's an ugly baby with pierced ears," the journalist said.
Katie's comments come after Kanye West's daughter was spotted over the weekend with pierced ears.
These types of comments aren't something new to Kimmy K, as it was only a few months ago that comedian Joan Rivers launched a verbal attack against her daughter.
According to reports by Radar Online, the E! presenter shocked her audience at the Saban Theatre in LA when she ranted about little Nori in January.
The Fashion Police host said: "That baby is ugly…I've never seen a six-month-old so desperately in need of a waxing."
Pretty harsh words from both ladies.
If we know anything about the Kardashian/West clan is that they will not take these comments lying down.
Katie, you'd best get an apology ready and waiting for them...Source