'I can't talk about him right now': Amy Adams breaks down in tears as she discusses PSH

She was one of many of Philip Seymour Hoffman's former co-stars who attended his wake and funeral after his tragic death from an apparent drug overdose.

And Amy Adams was understandably unable to contain her emotions when asked about her friend during an interview with James Lipton on Inside The Actor's Studio which aired on Wednesday night.

'Gosh, I wish you all could get the chance to work with him,' the 39-year-old Oscar nominated star told the audience of aspiring actors at Pace University in New York City. 'He was beautiful. He's a beautiful spirit and he had this unique ability to see people, to really see them - not look through them - he just really saw people. And he will be missed.'

The actress became emotional at the mention of her second Oscar nomination for Doubt, in which she starred alongside Meryl Streep and Hoffman.

'We've arrived at a difficult moment, of course, for you, for me, for the craft that we love, for the world in which we live,' Lipton told the audience as reported by Us Weekly. 'Fourteen years ago, I brought Philip Seymour Hoffman to this stage with the prediction that he would become the greatest actor of his generation.'

Amy struggled to contain her tears while attempting to discuss the talents of Streep and Hoffman in Doubt, putting her hands up to her face.

'Both Meryl and Philip have this ability to create... I'm sorry. I'm so sorry,' she said tearfully.

'That's alright. I'm so sorry,' said Lipton.

'To create a world - which as an audience you get to experience that - but you get to experience that in the room acting with them as well. And it's transformative.'

The clearly emotional actress continued: 'Sorry, I really... I just really loved him and I know so many people did. And I just don't know how much more I can talk about it right now. Sorry.'

The pair grew close when they made the 2008 drama Doubt, in which he played priest suspected of child abuse and she starred as a confrontational nun, and they also starred together in 2012's The Master.

Earlier this month, an eyewitness told Us Weekly: 'James Lipton asked her about working with Philip on Doubt and The Master… It hit a nerve with her. She was sobbing and couldn't finish most of her sentences.

Amy, 39, was one of the celebrities who attended the popular thespian's wake.

Cate Blanchett, Joaquin Phoenix, John C. Reilly and his longtime friend Justin Theroux were among other stars who attended the funeral home to pay their respects.

Amy, who is up for the best actress Oscar for her turn in American Hustle, was also nominated for her performance as the wife of Hoffman's charismatic cult leader Lancaster Dodd in The Master.

Philip was discovered dead on the floor of his bathroom on February 2 by his friend David Bar Katz after an apparent heroin overdose, and had been battling a relapse into drug and alcohol addiction after being sober for 20 years.