Her face is projected on 6 million viewers' HD-TV screens practically every morning.
And Live! with Kelly and Michael host Kelly Ripa has admitted she receives Botox injections every seven months in order to keep her pretty face looking its best.
'It's the Botox. Every seven months or so my eyelid skin rests on my eyelashes,' the 42-year-old star revealed in the February issue of Elle Magazine.
'So I feel like [Botox] makes my makeup artist's life easier, and it makes my eyes look a little more open on TV, which is where I happen to work right now.'
The three-time Emmy winner has even had injections in her armpits to prevent sweating, and she maintains her super-slim frame thanks to frequent SoulCycle spin classes.
Back when she starred on the soap All My Children, Kelly transformed lemons to lemonade whenever she received vicious, fat-shaming hate mail from fans.
The mother-of-three said: 'I feel like as long as you take ownership over your own flaws, it doesn’t hurt if someone else points them out.'
And with age comes more extensive medical examinations as Ripa discovered after has last mammogram for a life-insurance screening.
Kelly joked: 'I will say that it was the longest breast exam I’ve ever had. I was just like, "C'mon. I’m an A cup! This cannot go on this long!"'
And despite the bright designer duds she sports on her morning talk show, Ripa prides herself on her fuss-free style, which helps make her disappear in the Manhattan streets.
'I can walk out to the street and never be noticed. It’s my superpower: I’m invisible. I just look very normal and totally unremarkable,' the soap star said.
'Normally I’m in the same outfit every day, black jeans and a T-shirt—actually, this T-shirt, so I didn’t dress up that much. Sometimes I wear heels, because I happen to love heels, but if it’s freezing cold or boiling hot, it could easily be an Ugg boot or a flip-flop.'
The 64-inch-tall talk show host also opened up about her impressive 16-year marriage with Latin heartthrob Mark Consuelos.
'I actually call [Mark] Desi, because the thing about Desi was that as much attention as Lucy got, Desi was always in charge,' Kelly said referring to her 41-year-old Spanish-born beau.
The loved-up pair will sometimes have a part-time nanny watch their brood as they enjoy double dates with fellow celebrity couple Jerry and Jessica Seinfeld.
Blending in the crowd: The mother-of-three maintains her super-slim frame thanks to frequent SoulCycle spin classes
'I was drawn to Mark because he was positively an alpha male, and I didn’t think I would be drawn to that. But I just worship him. He makes me feel very safe,' said Ripa.
Kelly and Mark reside in New York's Soho neighbourhood with their three children - 15-year-old Michael, 11-year-old Lola, and Joaquin, who turns 10 next month.
Last year, the bubbly blonde was dubbed one of the most powerful people in media by The Hollywood Reporter.
But no matter how many accolades the former high school cheerleader receives, she still feels like a dork.
'I think that’s why people get me,' said the self-deprecating star.
'I would have styled my hair for 17 hours and it would still look very much like a Westminster show-dog. No matter how much I try to cool myself up, it’s never going to happen for me. But, like, am I dying to be cool? Yes, I’m dying to be.'
16 years strong: Kelly and her husband Mark Consuelos reside in New York's Soho neighbourhood with their three children - 15-year-old Michael, 11-year-old Lola, and Joaquin, who turns 10 next month
Elle magazine interview